Cellular and Mitochondrial Remodelling upon Defects in Iron- Sulfur Protein Biogenesis
نویسندگان
چکیده
CELLULAR AND MITOCHONDRIAL REMODELLING UPON DEFECTS IN IRONSULFUR PROTEIN BIOGENESIS Anja Hausmann , Birgit Samans , Roland Lill 1 and Ulrich Mühlenhoff 1 From Institut für Zytobiologie und Zytopathologie, Robert-Koch Strasse 6, 35032 Marburg 1 and Institut für Molekularbiologie und Tumorforschung, Emil-Mannkopf-Str. 2, Philipps-Universität Marburg, 35032 Marburg, Germany Running Title: Transcriptional response to Fe/S protein maturation defects in yeast Address correspondence to: Dr. Ulrich Mühlenhoff; Tel. (+49)-6421-2864171; Fax. (+49)-6421-2866414; E-mail: [email protected]
منابع مشابه
Cellular and mitochondrial remodeling upon defects in iron-sulfur protein biogenesis.
Biogenesis of iron-sulfur (Fe/S) proteins in eukaryotes is an essential process involving the mitochondrial iron-sulfur cluster (ISC) assembly and export machineries and the cytosolic iron/sulfur protein assembly (CIA) apparatus. To define the integration of Fe/S protein biogenesis into cellular homeostasis, we compared the global transcriptional responses to defects in the three biogenesis sys...
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